Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

Ken-Hong Lim; Jo-Ning Wu; To-Yu Huang; Jie-Yang Jhuang; Yu-Cheng Chang; Huan-Chau Lin; Yi-Hao Chiang; Ying-Wen Su; Caleb Gon-Shen Chen; Yi-Fang Chang; Johnson Lin

doi:10.1182/bloodadvances.2020003980

Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

Blood Adv. 2021 Mar 23;5(6):1733-1736. doi: 10.1182/bloodadvances.2020003980.

Authors

Ken-Hong Lim^{1

2

3}, Jo-Ning Wu³, To-Yu Huang³, Jie-Yang Jhuang⁴, Yu-Cheng Chang^{1

2

3}, Huan-Chau Lin^{1

3}, Yi-Hao Chiang^{1

3}, Ying-Wen Su^{1

2

3}, Caleb Gon-Shen Chen^{1

2

3

5

6}, Yi-Fang Chang^{1

2

3}, Johnson Lin¹

Affiliations

¹ Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan.
² Department of Medicine, MacKay Medical College, New Taipei City, Taiwan.
³ Good Clinical Research Center, Department of Medical Research, and.
⁴ Department of Pathology, MacKay Memorial Hospital, Taipei, Taiwan.
⁵ Department of Nursing, MacKay Junior College of Medicine, Nursing, and Management, New Taipei City, Taiwan; and.
⁶ Institute of Molecular Medicine, National Tsing-Hua University, Hsin-Chu, Taiwan.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Clonal Evolution
Humans
Mast Cells
Mastocytosis, Systemic* / diagnosis
Mastocytosis, Systemic* / genetics
Proto-Oncogene Proteins c-kit / genetics
Sequence Analysis, DNA

Substances

Proto-Oncogene Proteins c-kit