[Fertility preservation in testicular cancer patients]

Magy Onkol. 2021 Mar 17;65(1):53-57. Epub 2019 Aug 14.
[Article in Hungarian]

Abstract

Germ cell tumors of the testicle account for 1% of all tumors. Testicular cancer (TC) is the most common malignancy in men aged 15-35 years. Patients with TC have an excellent survival rate but often have not yet attempted to father children, and fertility is one of the main concerns of survivors, therefore it is important to preserve it. The most commonly used method is sperm banking. Retrospective analysis of the Hungarian data showed that in case of testicular cancer spermatogenesis is more impaired in the more advanced disease. No correlation was found among the histological types and the proportion of azoo- and oligozoospermia. The parameters of testicular cancer and non-Hodgkin lymphoma patients were worse compared to the normal population. Sperm cryopreservation prior to initiating life-saving cancer treatment offers men the best chance to father children and should be offered to all men with testicular cancer before chemotherapy, since cytostatic therapy may lead to infertility.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Cryopreservation
  • Fertility Preservation*
  • Humans
  • Male
  • Neoplasms*
  • Neoplasms, Germ Cell and Embryonal* / drug therapy
  • Retrospective Studies
  • Testicular Neoplasms* / drug therapy
  • Young Adult