Cartilage stem cells (CSCs) are cells that self-proliferate, have surface antigen expression, and have multidirectional differentiation potential in the articular cartilage. CSCs, as an ideal source of stem cells, has a good application prospect in stem cell therapy. This article reviews the CSCs markers, cartilage differentiation signaling pathway, and clinical treatment of osteoarthritis.
软骨干细胞是关节软骨中具有自我增殖、表面抗原表达特性及多向分化潜能的细胞，作为一种理想的干细胞来源，在干细胞治疗中有良好的应用前景。本文就软骨干细胞的标记、软骨分化信号通路、骨关节炎的临床治疗方法等研究进展进行综述。.
Keywords: cartilage ossification; cartilage stem cells; marker; osteoarthritis.