Outcomes of Patients with Sarcoma and COVID-19 Infection: A Single Institution Cohort Analysis

Cancer Invest. 2021 Apr;39(4):315-320. doi: 10.1080/07357907.2021.1903914. Epub 2021 Mar 26.

Abstract

Outcomes for patients (pts) with sarcoma and COVID-19 are unknown. This is a single institution retrospective study of adults with sarcoma and COVID-19. Ten pts [median age 60 (range 24-69)] were identified. Five were hospitalized; two died from COVID-19 complications; another died from sarcoma. Time between last systemic treatment dose and COVID-19 diagnosis was 6-41 days in pts who died. 5 underwent prior radiation (RT); time between RT and COVID-19 diagnosis was 20-62 days for pts who died. All three pts with WBC differential data (two died) were lymphopenic. Efforts to capture outcomes for a larger cohort are urgently needed.

Keywords: COVID-19; Sarcoma; cohort Study.

MeSH terms

  • Adult
  • Aged
  • COVID-19 / complications
  • COVID-19 / prevention & control*
  • COVID-19 / virology
  • COVID-19 Testing / methods
  • Chemoradiotherapy / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care / methods
  • Outcome Assessment, Health Care / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • SARS-CoV-2 / isolation & purification*
  • SARS-CoV-2 / physiology
  • Sarcoma / complications
  • Sarcoma / surgery
  • Sarcoma / therapy*
  • Soft Tissue Neoplasms / complications
  • Soft Tissue Neoplasms / surgery
  • Soft Tissue Neoplasms / therapy*
  • Survival Analysis
  • Young Adult