Aptasensors for mycotoxin detection: A review

Anal Biochem. 2022 May 1:644:114156. doi: 10.1016/j.ab.2021.114156. Epub 2021 Mar 11.

Abstract

Mycotoxins are toxic compounds produced by fungi, which represent a risk to the food and feed supply chain, having an impact on health and economies. A high percentage of feed samples have been reported to be contaminated with more than one type of mycotoxin. Systematic, cost-effective and simple tools for testing are critical to achieve a rapid and accurate screening of food and feed quality. In this review, we describe the various aptamers that have been selected against mycotoxins and their incorporation into optical and electrochemical aptasensors, outlining the strategies exploited, highlighting the advantages and disadvantages of each approach. The review also discusses the different materials used and the immobilization methods employed, with the aim of achieving the highest sensitivity and selectivity.

Keywords: Aflatoxin B1, B2; Fumonisin B1; Ochratoxin; Patulin; T-2 toxin; Zearalenone.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Food Contamination / analysis
  • Mycotoxins* / analysis

Substances

  • Mycotoxins