Gut microbiota, key to unlocking the door of diabetic kidney disease

Nephrology (Carlton). 2021 Aug;26(8):641-649. doi: 10.1111/nep.13874. Epub 2021 Mar 18.

Abstract

This review discusses the influence of gut microbiota dysbiosis on diabetic kidney disease through metabolite profile changes and immune and inflammatory mechanisms. We also elaborate on the mechanism of dysbiosis in the onset and development of other kidney diseases.

Keywords: diabetic kidney disease; gut microbiota; immune reaction; mechanism; metabolism.

Publication types

  • Review

MeSH terms

  • Diabetic Nephropathies / microbiology*
  • Dysbiosis / complications*
  • Gastrointestinal Microbiome*
  • Humans