Femtosecond ionization mass spectrometry for chromatographic detection

Totaro Imasaka; Tomoko Imasaka

doi:10.1016/j.chroma.2021.462023

Femtosecond ionization mass spectrometry for chromatographic detection

J Chromatogr A. 2021 Apr 12:1642:462023. doi: 10.1016/j.chroma.2021.462023. Epub 2021 Feb 27.

Authors

Totaro Imasaka¹, Tomoko Imasaka²

Affiliations

¹ Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan; Hikari Giken, Co., 2-10-30, Sakurazaka, Chuou-ku, Fukuoka 810-0024, Japan.
² Department of Environmental Design, Faculty of Design, Kyushu University, 4-9-1, Shiobaru, Minami-ku, Fukuoka 815-8540, Japan. Electronic address: imasaka@design.kyushu-u.ac.jp.

PMID: 33714081
DOI: 10.1016/j.chroma.2021.462023

Abstract

Mass spectrometry is now in widespread use for the detection of the analytes separated by chromatography. Electron ionization is the most frequently used method in mass spectrometry. However, this ionization technique sometimes suffers from extensive fragmentation of analytes, which makes identification difficult. A photoionization technique has been developed for suppressing this fragmentation and for subsequently observing a molecular ion. A variety of lasers have been employed for the sensitive and selective ionization of organic compounds. A femtosecond laser has a high peak power and is preferential for efficient ionization as well as for suppressing fragmentation, providing valuable information concerning molecular weight and chemical structure as well. In this review, we report on applications of femtosecond ionization mass spectrometry combined with gas chromatography.

Keywords: Femtosecond laser; Gas chromatography; Mass spectrometry; Molecular ion; Multiphoton ionization.

Publication types

Review

MeSH terms

Chromatography / methods*
Gas Chromatography-Mass Spectrometry
Mass Spectrometry / methods*
Polycyclic Aromatic Hydrocarbons / analysis
Spectrum Analysis, Raman
Thermodynamics

Substances

Polycyclic Aromatic Hydrocarbons