Co-location pattern mining plays an important role in spatial data mining. With the rapid growth of spatial datasets, the usefulness of co-location patterns is strongly limited by the huge amount of discovered patterns. Although several methods have been proposed to reduce the number of discovered patterns, these statistical algorithms are unable to guarantee that the extracted co-location patterns are user preferred. Therefore, it is crucial to help the decision maker discover his/her preferred co-location patterns via efficient interactive procedures. This article proposes a new interactive approach that enables the user to discover his/her preferred co-location patterns. First, we present a novel and flexible interactive framework to assist the user in discovering his/her preferred co-location patterns. Second, we propose using ontologies to measure the similarity of two co-location patterns. Furthermore, we design a pruning scheme by introducing a pattern filtering model for expressing the user's preference, to reduce the number of the final output. By applying our proposed approach over voluminous sets of co-location patterns, we show that the number of filtered co-location patterns is reduced to several dozen or less and, on average, 80% of the selected co-location patterns are user preferred.