Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shares common clinicopathologic features with other severe pulmonary illnesses. Hantavirus pulmonary syndrome was diagnosed in 2 patients in Arizona, USA, suspected of dying from infection with SARS-CoV-2. Differential diagnoses and possible co-infections should be considered for cases of respiratory distress during the SARS-CoV-2 pandemic.
Keywords: COVID-19; HPS; Peromyscus maniculatus; SARS-CoV-2; Sin Nombre virus; co-infection; coronavirus disease; differential diagnoses; hantavirus; hantavirus pulmonary syndrome; histopathology; immunohistochemical analysis; pathology; respiratory infections; severe acute respiratory syndrome coronavirus 2; vector-borne infections.