Complete nucleotide sequence of the neuraminidase gene of the human influenza virus A/Chile/1/83 (H1N1). Brief report

E Schreier; H Roeske; G Driesel; U Künkel; D R Petzold; R Berlinghoff; S Michel

doi:10.1007/BF01311076

Complete nucleotide sequence of the neuraminidase gene of the human influenza virus A/Chile/1/83 (H1N1). Brief report

Arch Virol. 1988;99(3-4):271-6. doi: 10.1007/BF01311076.

Authors

E Schreier¹, H Roeske, G Driesel, U Künkel, D R Petzold, R Berlinghoff, S Michel

Affiliation

¹ Department of Molecular Biology, Central Institute of Hygiene, Microbiology, and Epidemiology, Berlin, German Democratic Republic.

PMID: 3369945
DOI: 10.1007/BF01311076

Abstract

The complete nucleotide sequence of the neuraminidase (NA) gene of influenza virus A/Chile/1/83 (H1N1) has been determined after reverse transcription and cloning into the plasmid pAT 153/PvuII/8. The gene is 1461 nucleotides long and codes for a protein of 470 amino acids. The overall nucleotide and predicted amino acid sequence of the A/Chile/1/83 NA exhibits a high homology with other N1 neuraminidases. Hyper-variable regions concerning A to G exchanges are discussed.

MeSH terms

Amino Acid Sequence
Base Sequence
Cloning, Molecular
Genes, Viral*
Influenza A Virus, H1N1 Subtype*
Influenza A virus / genetics*
Molecular Sequence Data
Neuraminidase / genetics*

Substances

Neuraminidase