Optimal Cut-Off of Tricuspid Regurgitation Velocity According to the New Definition of Pulmonary Hypertension - Its Use in Predicting Pulmonary Hypertension

Keiko Sumimoto; Hidekazu Tanaka; Jun Mukai; Kentaro Yamashita; Yusuke Tanaka; Ayu Shono; Makiko Suzuki; Shun Yokota; Kensuke Matsumoto; Yu Taniguchi; Noriaki Emoto; Ken-Ichi Hirata

doi:10.1253/circrep.CR-20-0094

Optimal Cut-Off of Tricuspid Regurgitation Velocity According to the New Definition of Pulmonary Hypertension - Its Use in Predicting Pulmonary Hypertension

Circ Rep. 2020 Sep 24;2(10):625-629. doi: 10.1253/circrep.CR-20-0094.

Authors

Affiliation

¹ Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine Kobe Japan.

Abstract

Background: The 6th World Symposium on Pulmonary Hypertension proposed that precapillary pulmonary hypertension (PH) be defined as mean pulmonary arterial pressure (mPAP) >20 mmHg instead of mPAP ≥25 mmHg. Peak tricuspid regurgitation velocity (TRV) >3.4 m/s is widely used to predict PH, but it is unclear whether this value remains reliable for the new definition of PH. Methods and Results: We found that the optimal cut-off value of peak TRV for 511 PH patients was >2.8 m/s, with a sensitivity of 89.5%, specificity of 73.4%, and area under the curve of 0.89 (P<0.001). Conclusions: Based on the new definition of PH, TRV >2.8 m/s can be considered to indicate a high probability of PH.

Keywords: Echocardiography; Guidelines; Pulmonary hypertension.