A healthy full-term female neonate, aged 3 days and born by vaginal delivery (with a 1-minute Apgar score of 10 and a 5-minute Apgar score of 10), had unexpected cardiac and respiratory arrests in the early morning on day 3 after birth and recovered to spontaneous breathing and heartbeat after a 10-minute resuscitation. The child had poor response and convulsion after resuscitation. Blood gas analysis showed metabolic acidosis, and amplitude-integrated EEG showed a burst-suppression pattern. She was diagnosed with sudden unexpected postnatal collapse but improved after hypothermia and symptomatic/supportive treatment. This article reports the first case of sudden unexpected postnatal collapse in China and summarizes related risk factors, pathophysiological mechanisms, and preventive and treatment measures of this disorder.
3日龄健康足月顺产女婴，Apgar评分：1 min 10分、5 min 10分，生后第3天凌晨母婴同床时突发心跳、呼吸停止，经积极抢救恢复自主呼吸及心跳，复苏时间持续约10 min，复苏后患儿反应差并出现抽搐，血气分析提示代谢性酸中毒，振幅整合脑电图提示爆发-抑制图形，诊断为新生儿生后突发意外衰竭。该患儿经亚低温及对症支持治疗，病情好转。该文首次报道国内1例新生儿生后突发意外衰竭，并对其危险因素、病理生理机制、预防和治疗措施进行总结。