A Randomized Controlled Pilot Exercise and Protein Effectiveness Supplementation Study (EXPRESS) on Reducing Frailty Risk in Community-Dwelling Older People

J Nutr Gerontol Geriatr. 2021 Jan-Mar;40(1):26-45. doi: 10.1080/21551197.2021.1886222. Epub 2021 Mar 10.

Abstract

This pilot study aimed to examine the feasibility and effectiveness of a 6-months multi-component exercise program combined with twice daily consumption of either rice (RicePro) or whey-based (WheyPro) protein supplements (2 × 20 g of protein) on gait speed, grip strength and physical performance in community-dwelling pre-frail and frail older adults. Secondary outcomes included: frailty score, muscle mass, quality of life, nutritional intake, cognitive performance, depression and physical activity levels. A total of 70 participants (mean age 73.34 ± 6.85 years) were randomly allocated to either RicePro (n = 36) or WheyPro (n = 34). No adverse events were reported in regards to the exercise, however, several gastrointestinal symptoms were noted with the whey protein causing two-fold more symptoms compared to the rice protein. No differences were found between the groups (p > 0.05), except the total consumed energy (kJ) (p = 0.014) and fat (g) (p = 0.012) which was significantly lower in WheyPro. The results indicate that the quality of protein may not be as important as long as a sufficient amount is consumed.

Keywords: Frailty; multicomponent exercise; older adults; protein supplements.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Cognition
  • Dietary Proteins* / administration & dosage
  • Dietary Proteins* / adverse effects
  • Dietary Supplements
  • Eating* / physiology
  • Eating* / psychology
  • Exercise* / physiology
  • Exercise* / psychology
  • Female
  • Frailty* / diagnosis
  • Frailty* / physiopathology
  • Frailty* / therapy
  • Geriatric Assessment / methods
  • Humans
  • Independent Living
  • Male
  • Physical Functional Performance
  • Pilot Projects
  • Quality of Life
  • Walking Speed
  • Whey Proteins / administration & dosage
  • Whey Proteins / adverse effects

Substances

  • Dietary Proteins
  • Whey Proteins

Associated data

  • ANZCTR/ACTRN126160005214260