Abstract
Keywords:
glycoprotein; integrin; platelet activation; reactive oxygen species; thrombosis.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Blood Platelets / enzymology*
-
Enzyme Activation
-
Female
-
GTP-Binding Protein alpha Subunits, G12-G13 / genetics
-
GTP-Binding Protein alpha Subunits, G12-G13 / metabolism
-
Hydrogen Peroxide / metabolism*
-
Integrin beta3 / genetics
-
Integrin beta3 / metabolism*
-
Male
-
Mechanotransduction, Cellular*
-
Mice
-
Mice, Inbred C57BL
-
Mice, Knockout
-
NADPH Oxidase 2 / genetics
-
NADPH Oxidase 2 / metabolism*
-
NADPH Oxidases / metabolism
-
Phosphatidylinositol 3-Kinase / metabolism
-
Phosphorylation
-
Platelet Activation*
-
Platelet Factor 4 / genetics
-
Platelet Factor 4 / metabolism
-
Platelet Glycoprotein GPIIb-IIIa Complex / genetics
-
Platelet Glycoprotein GPIIb-IIIa Complex / metabolism*
-
Proto-Oncogene Proteins c-akt / metabolism
-
Stress, Mechanical
-
Syk Kinase / metabolism
Substances
-
Integrin beta3
-
Platelet Glycoprotein GPIIb-IIIa Complex
-
Platelet Factor 4
-
Hydrogen Peroxide
-
Cybb protein, mouse
-
NADPH Oxidase 2
-
NADPH Oxidases
-
neutrophil cytosolic factor 1
-
Phosphatidylinositol 3-Kinase
-
Syk Kinase
-
Syk protein, mouse
-
Proto-Oncogene Proteins c-akt
-
GTP-Binding Protein alpha Subunits, G12-G13