The influence of vitamin-C intake on blood glucose measurements in COVID-19 pandemic

J Infect Dev Ctries. 2021 Mar 7;15(2):209-213. doi: 10.3855/jidc.13960.

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) is declared as pandemic by the World Health Orgnazation (WHO) on March 2020. One of the heavily utilized measures during this pandemic is vitamin C (aka ascorbic acid). Unfortunately, vitamin C has been associated with glucose measurement interference and thus this study highlights the elevated levels of blood glucose correlated with the presence of vitamin C interference.

Methodology: Thirty samples were selected randomly and the blood glucose were measured prior and post the addition of spiked standard concentrations of vitamin C. The interference of vitamin C with glucose readings in COVID-19 pandemic were evaluated and observed employing the Auto Chemistry Analyzer machine.

Results: The addition of ascorbic acid (vitamin C) standards (spikes) into the isolated samples shows a correlated increment in the reading measures. Thereafter, the increments of Random Blood Sugar (RBS) readings after being spiked with the vitamin C standards shows a logarithmic correlation with good interesting R-squared (R2 = 0.9921).

Conclusions: The authors find that the presence of vitamin C in blood actively and significantly alters the glucose level readings especially with the highly consumption of vitamin C during the COVID-19 pandemic.

Keywords: Ascorbic Acid; Blood Glucose; COVID-19; Vitamin C; pandemic.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascorbic Acid / administration & dosage
  • Ascorbic Acid / blood*
  • Blood Glucose / analysis*
  • COVID-19
  • Humans

Substances

  • Blood Glucose
  • Ascorbic Acid