Cell Competition: A Choreographed Dance of Death

Ana Lima; Tristan A Rodriguez

doi:10.1016/j.cub.2021.01.017

Cell Competition: A Choreographed Dance of Death

Curr Biol. 2021 Mar 8;31(5):R255-R257. doi: 10.1016/j.cub.2021.01.017.

Authors

Ana Lima¹, Tristan A Rodriguez²

Affiliations

¹ National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: a.lima14@imperial.ac.uk.
² National Heart and Lung Institute, Imperial College London, London, UK. Electronic address: Tristan.rodriguez@imperial.ac.uk.

PMID: 33689726
DOI: 10.1016/j.cub.2021.01.017

Abstract

During cell competition fitter cells eliminate the weaker ones. New work identifies FGF21 as a factor that is secreted by the prospective loser cells of this competition and that acts to attract the winners towards them.

Publication types

Comment

MeSH terms

Animals
Apoptosis
Cell Competition*
Drosophila melanogaster*
Prospective Studies

Grants and funding

MR/P018467/1/MRC_/Medical Research Council/United Kingdom