SARS-CoV-2 and pediatric solid organ transplantation: Current knowns and unknowns

Pediatr Transplant. 2021 Aug;25(5):e13986. doi: 10.1111/petr.13986. Epub 2021 Mar 10.

Abstract

The COVID-19 pandemic has proven to be a challenge in regard to the clinical presentation, prevention, diagnosis, and management of SARS-CoV-2 infection among children who are candidates for and recipients of SOT. By providing scenarios and frequently asked questions encountered in routine clinical practice, this document provides expert opinion and summarizes the available data regarding the prevention, diagnosis, and management of SARS-CoV-2 infection among pediatric SOT candidates and recipients and highlights ongoing knowledge gaps requiring further study. Currently available data are still lacking in the pediatric SOT population, but data have emerged in both the adult SOT and general pediatric population regarding the approach to COVID-19. The document provides expert opinion regarding prevention, diagnosis, and management of SARS-CoV-2 infection among pediatric SOT candidates and recipients.

Keywords: COVID-19; SARS-CoV-2; SOT; children; pediatrics.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • COVID-19 / complications*
  • Child
  • Child, Preschool
  • End Stage Liver Disease / surgery*
  • False Positive Reactions
  • Female
  • Humans
  • Immunocompromised Host
  • Liver Transplantation / adverse effects*
  • Lung Transplantation / adverse effects*
  • Male
  • Organ Transplantation
  • Pandemics
  • Patient Safety
  • Postoperative Period
  • Reproducibility of Results
  • Reverse Transcriptase Polymerase Chain Reaction
  • Risk
  • Risk Factors
  • SARS-CoV-2*
  • Transplant Recipients*