Review of the Biological Activity of Maslinic Acid

Curr Drug Targets. 2021;22(13):1496-1506. doi: 10.2174/1389450122666210308111159.

Abstract

Since the discovery of (2α,3β)-2,3-dihydroxyolean-12-en-28-oic acid, also known as maslinic acid, many studies have examined its biological activity, which has been shown to promote health and resist various diseases. This article focuses on previous research on maslinic acid and mainly reviews its reported effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens. Maslinic acid exerts positive effects on both cell and animal models of disease. Although its mechanism of action has not yet been completely elucidated, maslinic acid is feasible as a nutritional additive and has the potential to be developed as a drug.

Keywords: Maslinic acid; cancer; cardiovascular diseases; diabetes; inflammation; neuroprotection; pathogens..

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Triterpenes* / pharmacology

Substances

  • Triterpenes
  • maslinic acid