COVID-19 or not COVID-19? Compared characteristics of patients hospitalized for suspected COVID-19

Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2023-2028. doi: 10.1007/s10096-021-04216-3. Epub 2021 Mar 8.

Abstract

During an epidemic period, we compared patients hospitalized for initial suspicion of COVID-19 but for whom an alternative diagnosis was finally retained (n = 152) with those who had COVID-19 (n = 222). Most common diagnoses were another infectious disease and heart failure. COVID-19-negative patients were more often active smokers had less often cough, fever, and digestive symptoms, as compared to the 222 COVID-19-positive patients. They had higher median neutrophil and lymphocyte counts and lower CRP level. In multivariate analysis, no current smoking, neurocognitive disorder, myalgia, and fibrinogen ≥4g/L were independently associated with a final diagnosis of COVID-19.

Keywords: COVID-19,; Differential diagnosis,; SARS-CoV2,; Tobacco.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • COVID-19 / diagnosis*
  • COVID-19 / therapy
  • COVID-19 / virology
  • Hospitalization
  • Humans
  • Male
  • Patients / statistics & numerical data
  • Retrospective Studies
  • SARS-CoV-2 / physiology