Low diversity of gut microbiota in the early phase of post-bone marrow transplantation increases the risk of chronic graft-versus-host disease

Bone Marrow Transplant. 2021 Jul;56(7):1728-1731. doi: 10.1038/s41409-021-01249-2. Epub 2021 Mar 8.

Tatsuya Konishi¹, Shinsuke Kusakabe², Akihisa Hino², Kyoko Inamoto¹, Kota Yoshifuji^{1

3}, Yuko Kiridoshi⁴, Kozue Takeshita⁵, Satoshi Sasajima⁵, Takashi Toya¹, Aiko Igarashi¹, Yuho Najima¹, Takeshi Kobayashi¹, Noriko Doki¹, Daisuke Motooka⁶, Shota Nakamura⁶, Masahiro Suyama^{7

8}, Wataru Suda^{8

9

10}, Atsushi Shiota⁴, Koji Atarashi⁴, Masahira Hattori^{8

9

10}, Kenya Honda^{5

8}, Takafumi Yokota², Kazuteru Ohashi¹, Hirohiko Shibayama², Kentaro Fukushima², Kazuhiko Kakihana¹¹

¹ Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.
² Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Osaka, Japan.
³ Department of Hematology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
⁴ JSR-Keio University Medical and Chemical Innovation Center (JKiC), Tokyo, Japan.
⁵ Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan.
⁶ Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
⁷ Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan.
⁸ RIKEN Center for Integrative Medical Sciences (IMS), Tokyo, Japan.
⁹ Graduate School of Advanced Science and Engineering, Waseda University, Tokyo, Japan.
¹⁰ Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.
¹¹ Hematology Division, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan. 0705kky@gmail.com.

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