Establishment of a personalized fetal growth curve model

Technol Health Care. 2021;29(S1):311-317. doi: 10.3233/THC-218028.

Abstract

Background: Fetal weight is one of the important indicators for judging whether fetal growth and development are normal. Fetal weight exceeding the normal range may lead to poor delivery outcomes.

Objective: We aimed to establish a personalized fetal growth curve in order to effectively monitor fetal growth during pregnancy. Fetal weight can be monitored while fetal growth and development are assessed.

Methods: This study retrospectively analyzed the birth weight and ultrasound database of 3,093 newborns delivered at normal term. The personalized fetal growth curve model was generated based on the birth weight formula established by Gardosi combined with the proportional weight equation.

Results: (1) The average birth weight of the single fetus at normal term was 3,457g. (2) According to the regression results of the proportion of fetal weight in full-term pregnancy and gestational week, the proportional weight equation is Weight% = 500.9 - 51.60GA + 1.727GA2- 0.01718GA3 (GA is gestational week), R2 is 98%, P< 0.001.

Conclusions: In this study, the normal birth weight of newborns and normal range of fetal weight can be estimated by using the personalized fetal growth curve model.

Keywords: Fetal weight; birth weight; fetal growth curve; normal range; proportional weight equation.

MeSH terms

  • Female
  • Fetal Development
  • Fetal Weight
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age*
  • Pregnancy
  • Retrospective Studies
  • Ultrasonography, Prenatal*