One year of SARS-CoV-2 evolution

Aiping Wu; Lulan Wang; Hang-Yu Zhou; Cheng-Yang Ji; Shang Zhou Xia; Yang Cao; Jing Meng; Xiao Ding; Sarah Gold; Taijiao Jiang; Genhong Cheng

doi:10.1016/j.chom.2021.02.017

One year of SARS-CoV-2 evolution

Cell Host Microbe. 2021 Apr 14;29(4):503-507. doi: 10.1016/j.chom.2021.02.017. Epub 2021 Feb 24.

Authors

Aiping Wu¹, Lulan Wang², Hang-Yu Zhou¹, Cheng-Yang Ji¹, Shang Zhou Xia², Yang Cao³, Jing Meng¹, Xiao Ding¹, Sarah Gold², Taijiao Jiang⁴, Genhong Cheng⁵

Affiliations

¹ Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.
² Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
³ Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, No. 29 Wangjiang Road, Chengdu 610064, China.
⁴ Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China; Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou 510005, China. Electronic address: taijiao@ibms.pumc.edu.cn.
⁵ Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: gcheng@mednet.ucla.edu.

Abstract

Since the outbreak of SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, the viral genome has acquired numerous mutations with the potential to increase transmission. One year after its emergence, we now further analyze emergent SARS-CoV-2 genome sequences in an effort to understand the evolution of this virus.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

COVID-19 / immunology
COVID-19 / virology*
Evolution, Molecular*
Genome, Viral*
Humans
Mutation*
SARS-CoV-2 / genetics*

Abstract

Publication types

MeSH terms

Grants and funding