Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins

Giuliana Fusco; Stefano Gianni

doi:10.3390/life11020140

Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins

Life (Basel). 2021 Feb 12;11(2):140. doi: 10.3390/life11020140.

Authors

Giuliana Fusco¹, Stefano Gianni²

Affiliations

¹ Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
² Istituto Pasteur-Fondazione Cenci Bolognetti and Istituto di Biologia e Patologia Molecolari del CNR, Dipartimento di Scienze Biochimiche "A. Rossi Fanelli," Sapienza Università di Roma, 00185 Rome, Italy.

Abstract

The discovery that a considerable fraction of the eukaryotic proteins lacks a well-defined three-dimensional structure in their native state has revolutionised our general understanding of proteins [...].

Publication types

Editorial