Are Sarcopenia and Cognitive Dysfunction Comorbid after Stroke in the Context of Brain-Muscle Crosstalk?

Sophia X Sui; Brenton Hordacre; Julie A Pasco

doi:10.3390/biomedicines9020223

Are Sarcopenia and Cognitive Dysfunction Comorbid after Stroke in the Context of Brain-Muscle Crosstalk?

Biomedicines. 2021 Feb 22;9(2):223. doi: 10.3390/biomedicines9020223.

Authors

Sophia X Sui¹, Brenton Hordacre², Julie A Pasco^{1

3

4

5}

Affiliations

¹ IMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, VIC 3220, Australia.
² IIMPACT in Health, Allied Health and Human Performance, University of South Australia, Adelaide, SA 5000, Australia.
³ Department of Medicine-Western Health, The University of Melbourne, St Albans, VIC 3021, Australia.
⁴ Barwon Health, University Hospital Geelong, Geelong, VIC 3220, Australia.
⁵ Department of Epidemiology and Preventive Medicine, Monash University, Prahran, VIC 3181, Australia.

Abstract

Stroke is a leading cause of death and disability and is responsible for a significant economic burden. Sarcopenia and cognitive dysfunction are common consequences of stroke, but there is less awareness of the concurrency of these conditions. In addition, few reviews are available to guide clinicians and researchers on how to approach sarcopenia and cognitive dysfunction as comorbidities after stroke, including how to assess and manage them and implement interventions to improve health outcomes. This review synthesises current knowledge about the relationship between post-stroke sarcopenia and cognitive dysfunction, including the physiological pathways, assessment tools, and interventions involved.

Keywords: cognitive dysfunction; post stroke; sarcopenia; stroke.

Publication types

Review

Abstract

Publication types

Grants and funding