Multidimensional Disadvantages of a Gluten-Free Diet in Celiac Disease: A Narrative Review

Nutrients. 2021 Feb 16;13(2):643. doi: 10.3390/nu13020643.

Abstract

A gluten-free diet is the mainstay method of treatment and the prevention of celiac disease complications. However, an inadequately balanced gluten-free diet can increase the risk of obesity, negatively affect glucose and lipid metabolism, and increase the risk of the metabolic syndrome. Therefore, an adequate nutritional counselling is necessary for patients diagnosed with celiac disease in order to prevent and treat the components of the metabolic syndrome.

Keywords: cardiovascular diseases; celiac disease; diabetes mellitus t.2; dyslipidemia; gluten-free diet; gut dysbiosis; gut microbiota; metabolic syndrome; microbiome; obesity.

Publication types

  • Review

MeSH terms

  • Celiac Disease / diet therapy*
  • Diet, Gluten-Free*
  • Glucose / metabolism
  • Humans
  • Lipid Metabolism
  • Patient Education as Topic

Substances

  • Glucose