Mesenchymal Stem/Stromal Cell Therapeutic Features: The Bridge between the Bench and the Clinic

J Clin Med. 2021 Feb 25;10(5):905. doi: 10.3390/jcm10050905.

Makram Merimi^{1

2}, Philippe Lewalle¹, Nathalie Meuleman¹, Douâa Moussa Agha¹, Hoda El-Kehdy³, Fatima Bouhtit^{1

2}, Sara Ayoub⁴, Arsène Burny⁵, Hassan Fahmi⁶, Laurence Lagneaux⁷, Mehdi Najar^{6

7}

¹ Laboratory of Experimental Hematology, Institut Jules Bordet, Université Libre de Bruxelles, 1000 Bruxelles, Belgium.
² Genetics and Immune Cell Therapy Unit, LBBES Laboratory, Faculty of Sciences, University Mohammed Premier, Oujda 60000, Morocco.
³ Laboratory of Pediatric Hepatology and Cell Therapy, UCLouvain, Institut de Recherche Expérimentale et Clinique, 1200 Brussels, Belgium.
⁴ Department of Prosthodontics, Faculty of Dental Medicine, Lebanese University, Hadath, 10999 Beirut, Lebanon.
⁵ Laboratory of Molecular and Cellular Biology, Faculté Universitaire des Sciences Agronomiques de Gembloux, 5030 Gembloux, Belgium.
⁶ Osteoarthritis Research Unit, University of Montreal Hospital Research Center, Montreal, QC H2X 0A9, Canada.
⁷ Laboratory of Clinical Cell Therapy, Institut Jules Bordet, Université Libre de Bruxelles, 1070 Brussels, Belgium.

Abstract

Mesenchymal stem/stromal cells (MSCs) are considered a relevant therapeutic product for various clinical applications [...].