Utility of a real-time fluorescence imaging device in guiding antibiotic treatment in superficial skin infections

Indian J Dermatol Venereol Leprol. 2022 May-Jun;88(4):509-514. doi: 10.25259/IJDVL_856_19.

Abstract

The prescription of antibiotics empirically without confirmation of an infective etiology is on the rise. Administration of appropriate antibiotics can be guided by real-time fluorescence imaging using a point-of-care device. These composite images show the presence, type and the burden of infection. The time saved by this method over microbiological testing, especially in resource-poor settings, can lead to a paradigm shift in treatment by facilitating prompt and adequate antimicrobial therapy, surgical debridement as well as follow-up. Thumbnail sketches of a series of four cases highlighting different scenarios in which a fluorescent imaging device utilizing artificial intelligence and machine learning was found useful is presented in this report.

Keywords: Antimicrobial stewardship; Illuminate; fluorescence imaging; infections; wound care.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents*
  • Artificial Intelligence
  • Humans
  • Optical Imaging / methods
  • Skin Diseases, Infectious* / drug therapy

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents