Two New Nonenolides from Diaporthe sp. SXZ-19, an Endophytic Fungus of Camptotheca Acuminata

Chem Biodivers. 2021 May;18(5):e2001055. doi: 10.1002/cbdv.202001055. Epub 2021 Mar 30.

Abstract

Two new nonenolides named diaportheolides A (1) and B (2) were isolated from the endophytic fungus Diaporthe sp. SXZ-19 of Camptotheca acuminata. The chemical structures of 1 and 2 were elucidated by spectroscopic analyses, including 1D- and 2D-NMR experiments and HR-ESI-MS data analysis. Their in vitro antibacterial activities are established to be insignificant.

Keywords: Diaporthe; antibacterial activity; endophytic fungus; nonenolide; spectroscopic analyses.

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification
  • Anti-Bacterial Agents / pharmacology*
  • Camptotheca / chemistry*
  • Microbial Sensitivity Tests
  • Molecular Conformation
  • Staphylococcus aureus / drug effects*

Substances

  • Anti-Bacterial Agents