The recent characteristics of influenza-related hospitalization in Japanese children

Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2011-2015. doi: 10.1007/s10096-021-04208-3. Epub 2021 Mar 4.

Abstract

We investigated the recent epidemiology and characteristics of influenza-related hospitalization in Japanese children. This study included 3741 children with influenza. Children hospitalized for febrile seizures (FS) induced by etiologies other than influenza also served as a disease control. Most outpatients (92.8%) visited our hospital with complaints of respiratory symptoms, whereas FS were the most predominant symptoms of inpatients (58/154, 37.7%). Children with influenza-induced FS were significantly older than those with FS induced by other etiologies (P <0.001). Although the characteristics of severe influenza may vary throughout the world, the analysis of influenza-induced neurological disorders is important for understanding its epidemiology.

Keywords: Febrile seizures; Geographical difference; Hospitalization; Influenza virus; Older children.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Influenza A virus / genetics
  • Influenza A virus / pathogenicity
  • Influenza, Human / complications*
  • Influenza, Human / epidemiology
  • Japan
  • Male
  • Respiratory Tract Infections / epidemiology*
  • Respiratory Tract Infections / virology
  • Retrospective Studies
  • Seizures, Febrile / epidemiology*
  • Seizures, Febrile / etiology