Coronary Sinus Reducer for the Treatment of Chronic Refractory Angina: Will This Challenge the Treatment of Coronary Chronic Total Occlusions?

Curr Cardiol Rep. 2021 Mar 2;23(4):31. doi: 10.1007/s11886-021-01463-w.

Abstract

Purpose of review: The prevalence of angina despite optimal medical therapy is high among patients with coronary chronic total occlusions. Despite advancements in techniques and operator's experience, percutaneous revascularization of coronary chronic total occlusions is still associated with a not negligible risk of failures and complications. The Coronary Sinus Reducer, a new device developed to improve angina, has shown promising results in terms of efficacy and safety in patients with refractory symptoms. The aim of this review is to summarize the evidence so far available and to guide clinicians in the selection of patients with chronic total occlusions that could benefit more from Coronary Sinus Reducer implantation.

Recent findings: A recently published study suggests a clear value of this device in patients with chronic total occlusions. This is likely to be related to the presence of a well-developed collateral circulation. A careful evaluation of risks and benefits of both myocardial revascularization and Coronary Sinus Reducer implantation should be done in all the cases in order to better define the optimal strategy for the patient. The Coronary Sinus Reducer implantation has a rationale in patients with chronic total occlusion as an alternative or additional therapy to myocardial revascularization.

Keywords: Chronic ischemia; Coronary Sinus Reducer; Coronary chronic total occlusions; Refractory angina.

Publication types

  • Review

MeSH terms

  • Angina Pectoris
  • Coronary Occlusion* / surgery
  • Coronary Sinus* / surgery
  • Humans
  • Percutaneous Coronary Intervention*
  • Treatment Outcome