The influence of soy protein hydrolysate (SPH) addition to infant formula powder on Streptococcus thermophilus proliferation and metabolism

Zhi-Hui Sun; Ming-Jing Yao; Xin Bian; Qing-Qi Guo; Hua-Nan Guan; Yang Yang; Bing Wang; Yan-Guo Shi; Wojciech Piekoszewski; Xiao-Wan Yang; Na Zhang

doi:10.1016/j.foodres.2020.110103

The influence of soy protein hydrolysate (SPH) addition to infant formula powder on Streptococcus thermophilus proliferation and metabolism

Food Res Int. 2021 Mar:141:110103. doi: 10.1016/j.foodres.2020.110103. Epub 2021 Jan 5.

Authors

Affiliations

¹ Key Laboratory of Food Science and Engineering of Heilongjiang Province, Harbin University of Commerce, 36# No.138, TongDa Street, DaoLi District, Harbin 150076, PR China.
² Key Laboratory of Food Science and Engineering of Heilongjiang Province, Harbin University of Commerce, 36# No.138, TongDa Street, DaoLi District, Harbin 150076, PR China; Shandong Provincial Key Laboratory of Food and Fermentation Engineering, Shandong Food Ferment Industry Research & Design Institute, Qilu University of Technology (Shandong Academy of Sciences), No.41, JieFang Road, LiXia District, Jinan 250013, PR China.
³ Forestry School, Northeast Forestry University, No.26, HeXing Street, XiangFang District, Harbin 150040, PR China.
⁴ Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University, 2 Gronostajowa, 30-868 Krakow, Poland; School of Biomedicine, Far Eastern Federal University, FEFU Campus, Russian Island, Vladivostok, Russian Federation.
⁵ Key Laboratory of Food Science and Engineering of Heilongjiang Province, Harbin University of Commerce, 36# No.138, TongDa Street, DaoLi District, Harbin 150076, PR China; Shanghai Special Favor Biotechnology Co., Ltd, No. 56, JunGong Road, Yangpu District, Shanghai 200433, PR China.
⁶ Key Laboratory of Food Science and Engineering of Heilongjiang Province, Harbin University of Commerce, 36# No.138, TongDa Street, DaoLi District, Harbin 150076, PR China. Electronic address: foodzhangna@163.com.

PMID: 33641970
DOI: 10.1016/j.foodres.2020.110103

Abstract

Nowadays, more and more infants are getting allergic to cow's milk protein, so it is urgent to search for infant formula powder with milk protein alternatives. In the present work, soy protein hydrolysate (SPH) was added to protein-free infant formula powder and the effects of SPH addition on proliferation and metabolism of Streptococcus thermophilus were studied. Compared with commercially available infant formula powder (CK) and protein-free milk powder (BK), the infant formula powder with 20% SPH significantly enhanced the proliferation of S. thermophilus in MRS medium, resulting in a higher cell density and greater viable counts. Moreover, the influence of SPH on the metabolism of S. thermophilus was investigated by analyzing the content of seven organic acids and H₂O₂ in the medium_. The higher content of organic acids and H₂O₂ is consistent with the stronger antibacterial activity to Escherichia coli. As a consequence, the addition of SPH to infant formula powder can effectively promote the growth of probiotics and SPH may be a promising protein alternative in the infant formula powder.

Keywords: Allergy; Bacterial metabolism; Dry milk; Probiotic bacterium; Soy protein hydrolysate (SPH).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cattle
Cell Proliferation
Female
Humans
Hydrogen Peroxide
Infant
Infant Formula*
Milk Hypersensitivity*
Powders
Protein Hydrolysates
Streptococcus thermophilus

Substances

Powders
Protein Hydrolysates
Hydrogen Peroxide