Aging Immune System in Acute Ischemic Stroke: A Transcriptomic Analysis

Stroke. 2021 Apr;52(4):1355-1361. doi: 10.1161/STROKEAHA.120.032040. Epub 2021 Mar 1.

¹ Division of Neurology, Department of Medicine (G.P.S., S.Z., D.M., G.J.), Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
² Neuroscience and Mental Health Institute (J.K.-T., G.J.), Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
³ Department of Medical Microbiology and Immunology (S.F.), Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
⁴ Department of Neurology, University of California, Davis, Sacramento (B.S., B.P.A., F.R.S., G.J.).

Abstract

[Figure: see text].

Keywords: aging; immune system; immunosenescence; inflammation; ischemic stroke; leukocytes; stroke outcome.