A review of the presence of SARS-CoV-2 RNA in wastewater and airborne particulates and its use for virus spreading surveillance

Uttpal Anand; Bashir Adelodun; Alberto Pivato; S Suresh; Omkar Indari; Shweta Jakhmola; Hem Chandra Jha; Pawan Kumar Jha; Vijay Tripathi; Francesco Di Maria

doi:10.1016/j.envres.2021.110929

A review of the presence of SARS-CoV-2 RNA in wastewater and airborne particulates and its use for virus spreading surveillance

Environ Res. 2021 May:196:110929. doi: 10.1016/j.envres.2021.110929. Epub 2021 Feb 25.

Authors

Affiliations

¹ Department of Life Sciences, National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
² Department of Agricultural and Biosystems Engineering, University of Ilorin, PMB 1515, Ilorin, Nigeria; Department of Agricultural Civil Engineering, Kyungpook National University, Daegu, Republic of Korea.
³ DICEA - Department of Civil, Environmental and Architectural Engineering, University of Padova, Via Marzolo 9, 35131, Padova, Italy.
⁴ Department of Chemical Engineering, Maulana Azad National Institute of Technology, Bhopal, 462 003, Madhya Pradesh, India.
⁵ Discipline of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore, 453552, Indore, Madhya Pradesh, India.
⁶ Centre for Environmental Studies, University of Allahabad, Prayagraj, 211002, Uttar Pradesh, India.
⁷ Department of Molecular and Cellular Engineering, Jacob Institute of Biotechnology and Bioengineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, Uttar Pradesh, India. Electronic address: francesco.dimaria@unipg.it.
⁸ LAR(5) Laboratory - Dipartimento di Ingegneria - University of Perugia, via G. Duranti 93, 06125, Perugia, Italy. Electronic address: francesco.dimaria@unipg.it.

Abstract

According to the WHO, on October 16, 2020, the spreading of the SARS-CoV-2, responsible for the COVID-19 pandemic, reached 235 countries and territories, and resulting in more than 39 million confirmed cases and 1.09 million deaths globally. Monitoring of the virus outbreak is one of the main activities pursued to limiting the number of infected people and decreasing the number of deaths that have caused high pressure on the health care, social, and economic systems of different countries. Wastewater based epidemiology (WBE), already adopted for the surveillance of life style and health conditions of communities, shows interesting features for the monitoring of the COVID-19 diffusion. Together with wastewater, the analysis of airborne particles has been recently suggested as another useful tool for detecting the presence of SARS-CoV-2 in given areas. The present review reports the status of research currently performed concerning the monitoring of SARS-CoV-2 spreading by WBE and airborne particles. The former have been more investigated, whereas the latter is still at a very early stage, with a limited number of very recent studies. Nevertheless, the main results highlights in both cases necessitate more research activity for better understating and defining the biomarkers and the related sampling and analysis procedures to be used for this important aim.

Keywords: Airborne particles; Biomarkers; COVID-19; SARS-CoV-2; Wastewater; Wastewater-based epidemiology (WBE).

Publication types

Review

MeSH terms

COVID-19*
Humans
Pandemics
RNA, Viral
SARS-CoV-2*
Wastewater

Substances

RNA, Viral
Waste Water