Acute myelopathies associated to SARS-CoV-2 infection: Viral or immune-mediated damage?

Isabella Canavero; Francesca Valentino; Elena Colombo; Diego Franciotta; Delfina Ferrandi; Marco Mussa; Rodolfo Schizzi; Kalliopi Marinou; Carla Zanferrari; Pietro Businaro; Sabrina Ravaglia; Paolo Prunetti; Giuseppe Cosentino; Lisa Maria Farina; Elisa Rognone; Anna Pichiecchio; Giuseppe Micieli

doi:10.1016/j.tmaid.2021.102000

Acute myelopathies associated to SARS-CoV-2 infection: Viral or immune-mediated damage?

Travel Med Infect Dis. 2021 Mar-Apr:40:102000. doi: 10.1016/j.tmaid.2021.102000. Epub 2021 Feb 25.

Authors

Isabella Canavero¹, Francesca Valentino², Elena Colombo³, Diego Franciotta⁴, Delfina Ferrandi⁵, Marco Mussa⁶, Rodolfo Schizzi⁷, Kalliopi Marinou⁸, Carla Zanferrari⁹, Pietro Businaro¹⁰, Sabrina Ravaglia², Paolo Prunetti¹¹, Giuseppe Cosentino¹², Lisa Maria Farina¹³, Elisa Rognone¹³, Anna Pichiecchio¹⁴, Giuseppe Micieli²

Affiliations

¹ Cerebrovascular Unit, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy. Electronic address: isabella.canavero@istituto-besta.it.
² Emergency Neurology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.
³ Multiple Sclerosis Center, IRCCS C. Mondino Foundation, Pavia, Italy.
⁴ Neuroimmunology Unit, IRCCS C. Mondino Foundation, Pavia, Italy; Autoimmunology Laboratory, IRCCS Ospedale Policlinico San Martino, Genoa, Italy (current address).
⁵ S.C. Neurologia, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy; U.O. Neurologia, Ospedale Santo Spirito, Casale Monferrato, Italy (current address).
⁶ S.C. Malattie Infettive, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
⁷ S.C. Radiologia, Azienda Ospedaliera SS, Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
⁸ Neurorehabilitation Department, IRCCS Istituti Clinici Scientifici, Milan, Italy.
⁹ UOC Neurologia / Stroke Unit, ASST Melegnano-Martesana, Milan, Italy.
¹⁰ Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
¹¹ Clinical Neurophysiology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.
¹² Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; Clinical Neurophysiology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.
¹³ Neuroradiology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.
¹⁴ Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; Neuroradiology Unit, IRCCS C. Mondino Foundation, Pavia, Italy.

No abstract available

Keywords: Acute flaccid paraplegia; Acute myelopathy; COVID-19; Demyelinating myelitis; Polio-like syndrome; SARS-CoV-2.

Publication types

Case Reports
Letter

MeSH terms

Adult
Aged
COVID-19 / complications*
COVID-19 / diagnosis
COVID-19 / immunology*
Female
Humans
Male
Middle Aged
Myelitis / diagnosis
Myelitis / virology
Myelitis, Transverse / diagnosis
Myelitis, Transverse / virology
SARS-CoV-2 / isolation & purification
Spinal Cord Diseases / diagnostic imaging
Spinal Cord Diseases / immunology*
Spinal Cord Diseases / virology*