Biofuels for a sustainable future

Cell. 2021 Mar 18;184(6):1636-1647. doi: 10.1016/j.cell.2021.01.052. Epub 2021 Feb 26.

Abstract

Rapid increases of energy consumption and human dependency on fossil fuels have led to the accumulation of greenhouse gases and consequently, climate change. As such, major efforts have been taken to develop, test, and adopt clean renewable fuel alternatives. Production of bioethanol and biodiesel from crops is well developed, while other feedstock resources and processes have also shown high potential to provide efficient and cost-effective alternatives, such as landfill and plastic waste conversion, algal photosynthesis, as well as electrochemical carbon fixation. In addition, the downstream microbial fermentation can be further engineered to not only increase the product yield but also expand the chemical space of biofuels through the rational design and fine-tuning of biosynthetic pathways toward the realization of "designer fuels" and diverse future applications.

Keywords: alternative energy; biofuels; climate change; metabolic engineering; synthetic biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Biofuels / analysis*
  • Biosynthetic Pathways
  • Carbon Cycle
  • Humans
  • Lignin / metabolism
  • Sustainable Development*
  • Waste Products

Substances

  • Biofuels
  • Waste Products
  • lignocellulose
  • Lignin