Downregulated miR-451a as a feature of the plasma cfRNA landscape reveals regulatory networks of IL-6/IL-6R-associated cytokine storms in COVID-19 patients

Affiliations

• ¹ Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China.
• ² NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
• ³ BGI-Shenzhen, Shenzhen, China.
• ⁴ BGI Education Center, University of Chinese Academic of Sciences, Shenzhen, China.
• ⁵ Shenzhen Bay Laboratory, Shenzhen, China.
• ⁶ BGI College, Zhengzhou University, Zhengzhou, China.
• ⁷ School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China.
• ⁸ CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
• ⁹ Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China. zhangsg302@hotmail.com.
• ¹⁰ NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. gaofu@chinacdc.cn.
• ¹¹ School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China. gaofu@chinacdc.cn.
• ¹² BGI-Shenzhen, Shenzhen, China. liulongqi@genomics.cn.
• ¹³ Shenzhen Bay Laboratory, Shenzhen, China. liulongqi@genomics.cn.
• ¹⁴ NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China. liujun@ivdc.chinacdc.cn.
• ¹⁵ BGI-Shenzhen, Shenzhen, China. sunhaixi@genomics.cn.