Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination

Org Lett. 2021 Mar 19;23(6):2094-2098. doi: 10.1021/acs.orglett.1c00251. Epub 2021 Feb 26.

Abstract

A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.

Publication types

  • Research Support, Non-U.S. Gov't