Guidelines for the Management of Children and Adolescent with COVID-19: protocol for an update

Qi Zhou; Weiguo Li; Siya Zhao; Qinyuan Li; Qianling Shi; Zijun Wang; Hui Liu; Xiao Liu; Janne Estill; Zhengxiu Luo; Qiu Li; Kehu Yang; Enmei Liu; Yaolong Chen

doi:10.21037/tp-20-290

Guidelines for the Management of Children and Adolescent with COVID-19: protocol for an update

Transl Pediatr. 2021 Jan;10(1):177-182. doi: 10.21037/tp-20-290.

Authors

Qi Zhou^{1

2}, Weiguo Li³, Siya Zhao⁴, Qinyuan Li³, Qianling Shi¹, Zijun Wang², Hui Liu⁴, Xiao Liu⁴, Janne Estill^{5

6}, Zhengxiu Luo³, Qiu Li⁷, Kehu Yang^{1

2

8

9

10

11

12}, Enmei Liu³, Yaolong Chen^{2

8

9

10

11

12}

Affiliations

¹ The First School of Clinical Medicine, Lanzhou University, Lanzhou, China.
² Evidence-based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
³ Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China.
⁴ School of Public Health, Lanzhou University, Lanzhou, China.
⁵ Institute of Global Health, University of Geneva, Geneva, Switzerland.
⁶ Institute of Mathematical Statistics and Actuarial Science, University of Bern, Bern, Switzerland.
⁷ Department of Nephrology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing, China.
⁸ WHO Collaborating Centre for Guideline Implementation and Knowledge Translation, Lanzhou, China.
⁹ GIN Asia, Lanzhou, China.
¹⁰ Chinese GRADE Centre, Lanzhou, China.
¹¹ Lanzhou University, an Affiliate of the Cochrane China Network, Lanzhou, China.
¹² Key Laboratory of Evidence Based Medicine & Knowledge Translation of Gansu Province, Lanzhou, China.

Abstract

Background: Coronavirus disease 2019 (COVID-19) has become a constant threat to people's lives, bringing huge challenges to the global public health and medical service system. In order to ensure the timeliness and reliability of the recommendations in guidelines, the working group of the Rapid Advice Guidelines for Management of Children with COVID-19 decided to update the guideline to incorporate the latest evidence to guide the management of COVID-19 in children and adolescent.

Methods: We will update the guidelines, originally developed as a rapid advice guideline, into a standard guideline. We will follow the clinical practice guideline (CPG) update manuals of the National Institute for Health and Clinical Excellence (NICE) and the Spanish National Health System (SNHS). The updated guidelines will also follow the RIGHT (Reporting Items for Practice Guidelines in Healthcare) checklist and Checklist for the Reporting of Updated Guidelines (CheckUp).

Discussion: Through systematic search, evaluation and grading of the best available relevant clinical evidence, combined with the experience of frontline clinical experts in the fight against the epidemic and the wishes of patients and their caretakers, we will update our previous rapid advice guidelines into a high-quality, implementable standard guidelines for the management of COVID-19 in children and adolescent.

Trial registration: The standard guideline update has been registered at the International Practice Guidelines Registry Platform (http://guidelines-registry.cn/?lang=en, registration No. IPGRP-2020CN101).

Keywords: Coronavirus disease 2019 (COVID-19); children; protocol; standard guideline.