Clinical Efficacy of Intravenous Immunoglobulins in Management of Toxic Shock Syndrome: An Updated Literature Review

Sana Amreen; Simrandeep K Brar; Sumera Perveen; Muhammad Reza Chaudhry; Sarah AlBabtain; Safeera Khan

doi:10.7759/cureus.12836

Clinical Efficacy of Intravenous Immunoglobulins in Management of Toxic Shock Syndrome: An Updated Literature Review

Cureus. 2021 Jan 21;13(1):e12836. doi: 10.7759/cureus.12836.

Authors

Sana Amreen¹, Simrandeep K Brar¹, Sumera Perveen^{2

3}, Muhammad Reza Chaudhry^{4

5}, Sarah AlBabtain⁶, Safeera Khan¹

Affiliations

¹ Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
² Internal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
³ Family Medicine, Ibne Sina Hospital Parco MCR, Multan, PAK.
⁴ Psychiatry, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
⁵ Public Health and Preventive Medicine, St. George's University School of Medicine, St. George's, GRD.
⁶ Psychiatry and Behavioral Sciences, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Abstract

Toxic shock syndrome (TSS) is an uncommon complication of infection caused by streptococci and staphylococci. It is associated with a high mortality rate. When evaluating patients with shock symptoms from skin or soft tissue sources, a high index of suspicion for TSS must be maintained. Prompt diagnosis and integrative management with surgical intervention, antibiotics, hemodynamic stabilization, and adjuvants like intravenous immunoglobulins improve survival.

Keywords: and treatment of tss; intravenous immunoglobulins (ivig); management of toxic shock syndrome; staphylococcal tss; streptococcal tss; toxic shock syndrome (tss).

Publication types

Review