Circulating Wnt Ligands Activate the Wnt Signaling Pathway in Mature Erythrocytes

Arterioscler Thromb Vasc Biol. 2021 May 5;41(5):e243-e264. doi: 10.1161/ATVBAHA.120.315413. Epub 2021 Feb 25.

Abstract

[Figure: see text].

Keywords: Wnt signaling; cytoskeleton; deformability; erythrocytes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actin Cytoskeleton / genetics
  • Actin Cytoskeleton / metabolism*
  • Animals
  • Cell Survival
  • Erythrocyte Deformability*
  • Erythrocyte Transfusion
  • Erythrocytes / metabolism*
  • Female
  • Humans
  • Ligands
  • Lymphocytes / metabolism
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Monocytes / metabolism
  • Receptors, Wnt / blood*
  • Receptors, Wnt / genetics
  • Time Factors
  • Wnt Signaling Pathway*
  • Wnt-5a Protein / blood
  • Wnt-5a Protein / genetics
  • Wnt3A Protein / blood
  • Wnt3A Protein / genetics

Substances

  • Ligands
  • Receptors, Wnt
  • WNT3A protein, human
  • WNT5A protein, human
  • Wnt-5a Protein
  • Wnt3A Protein
  • Wnt3a protein, mouse
  • Wnt5a protein, mouse