Abstract
Risk of severe coronavirus disease 2019 (COVID-19) after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increased in patients with certain comorbidities, including chronic obstructive pulmonary disease (COPD). By contrast, epidemiological data from many (but not all) countries indicate a low prevalence of asthma among patients with severe COVID-19. This reduced risk of severe COVID-19 may apply specifically to patients with the type 2 asthma endotype, which is most common in childhood asthma.
MeSH terms
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Angiotensin-Converting Enzyme 2 / genetics
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Angiotensin-Converting Enzyme 2 / metabolism
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Asthma / epidemiology*
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Asthma / immunology*
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COVID-19 / epidemiology*
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Eosinophilia / immunology
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Humans
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Interleukin-13 / immunology
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Interleukin-4 / immunology
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Interleukin-5 / immunology
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Phenotype
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Pulmonary Disease, Chronic Obstructive / epidemiology
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Pulmonary Disease, Chronic Obstructive / immunology
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RNA, Messenger / metabolism
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Receptors, Coronavirus / genetics
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Receptors, Coronavirus / metabolism
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Risk
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SARS-CoV-2
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Severity of Illness Index
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Th1 Cells / immunology
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Th17 Cells / immunology
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Th2 Cells / immunology
Substances
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Interleukin-13
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Interleukin-5
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RNA, Messenger
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Receptors, Coronavirus
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Interleukin-4
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Angiotensin-Converting Enzyme 2