Abstract
A new study shows that the pioneer transcription factor BLMP-1 governs the cyclic transcriptional output of hundreds of genes during Caenorhabditis elegans larval development. BLMP-1 is also critical for restarting the proper developmental dynamics of gene expression after nutritionally induced developmental arrest.
Copyright © 2021 Elsevier Inc. All rights reserved.
MeSH terms
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Animals
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Caenorhabditis elegans / genetics
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Caenorhabditis elegans / metabolism
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Caenorhabditis elegans Proteins* / genetics
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Caenorhabditis elegans Proteins* / metabolism
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Gene Expression
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Gene Expression Regulation, Developmental
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Transcription Factors / genetics
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Transcription Factors / metabolism
Substances
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Caenorhabditis elegans Proteins
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Transcription Factors