Current perspectives on galvanic vestibular stimulation in the treatment of Parkinson's disease

Expert Rev Neurother. 2021 Apr;21(4):405-418. doi: 10.1080/14737175.2021.1894928. Epub 2021 Mar 4.

Abstract

Introduction: Galvanic vestibular stimulation (GVS) is a noninvasive technique that activates vestibular afferents, influencing activity and oscillations in a broad network of brain regions. Several studies have suggested beneficial effects of GVS on motor symptoms in Parkinson's Disease (PD).Areas covered: A comprehensive overview of the stimulation techniques, potential mechanisms of action, challenges, and future research directions.Expert opinion: This emerging technology is not currently a viable therapy. However, a complementary therapy that is inexpensive, easily disseminated, customizable, and portable is sufficiently enticing that continued research and development is warranted. Future work utilizing biomedical engineering approaches, including concomitant functional neuroimaging, have the potential to significantly increase efficacy. GVS could be explored for other PD symptoms including orthostatic hypotension, dyskinesia, and sleep disorders.

Keywords: Galvanic vestibular stimulation; eeg; fMRI; motor function; neuromodulation; parkinson’s disease; the vestibular system.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain
  • Electric Stimulation
  • Humans
  • Parkinson Disease* / therapy
  • Vestibule, Labyrinth*