Siderosis Bulbi

Excerpt

Siderosis bulbi refers to the pigmentary, degenerative process of the eye following chronic retention of an iron-containing intra-ocular foreign body (IOFB). It can also occur due to iron derived from the blood. First described by Bunge in 1890, siderosis bulbi has an affinity for ocular structures of epithelial origin such as the cornea, iris, lens, trabecular meshwork, and retina. Iron deposition at these sites leads to the altered morphology of the tissues. A comprehensive clinical evaluation is thus vital to timely detect the development of ocular siderosis and effectively manage these patients without delay.