The associations of pregnancy-related symptoms with health-related quality of life at midpregnancy: the PregnActive project

J Matern Fetal Neonatal Med. 2022 Dec;35(25):5337-5345. doi: 10.1080/14767058.2021.1879040. Epub 2021 Feb 21.

Abstract

Aim: To analyze the associations between the wide range of pregnancy-related symptoms and health-related quality of life.

Material and methods: A cross-sectional study was developed among 155 healthy low-risk pregnant women, aged 18-45 years, participated in the study at midpregnancy. Health-related quality of life and pregnancy symptoms were assessed using the Medical Outcome Study 36-item short form questionnaire and the Pregnancy Symptoms Inventory, respectively. Simple correlations, hierarchical linear regressions and standard multiple regressions were performed.

Results: Significant correlations, after adjusting for sociodemographic and anthropometric characteristics, were found between five pregnancy-related symptoms and physical component of health-related quality of life and between thirteen pregnancy-related symptoms and mental component. However, when all pregnancy symptoms were entered simultaneously into a multiple regression model, back pain and shortness of breath on the physical components, and feeling depressed and anxiety on the mental component were the main explanatory factors of health-related quality of life.

Conclusion: Among the wide range of pregnancy-related symptoms, back pain, hip or pelvic pain, shortness of breath, and feeling depressed and anxiety are the main symptoms affecting the physical and the mental components of health-related quality of life, respectively. An early detection of the pregnancy-related symptoms that may affect health-related quality of life enables early interventions aimed at ameliorating their negative impact on health-related quality of life and daily living activities at midpregnancy.

Keywords: Pregnancy; health-related quality of life; nursing; pregnancy symptoms; women’s health.

MeSH terms

  • Anxiety* / epidemiology
  • Cross-Sectional Studies
  • Dyspnea
  • Female
  • Humans
  • Pregnancy
  • Quality of Life*
  • Surveys and Questionnaires