Management of Coronavirus Disease 2019 (COVID-19) Pandemic: From Diagnosis to Treatment Strategies

Zhina Hadisi; Tavia Walsh; Seyed Mohammad Hossein Dabiri; Amir Seyfoori; David Hamdi; Bahram Mirani; Erik Pagan; Armando Jardim; Mohsen Akbari

doi:10.1002/adtp.202000173

Management of Coronavirus Disease 2019 (COVID-19) Pandemic: From Diagnosis to Treatment Strategies

Adv Ther (Weinh). 2021 Mar;4(3):2000173. doi: 10.1002/adtp.202000173. Epub 2020 Dec 16.

Authors

Zhina Hadisi¹, Tavia Walsh¹, Seyed Mohammad Hossein Dabiri¹, Amir Seyfoori¹, David Hamdi¹, Bahram Mirani^{2

3

4}, Erik Pagan¹, Armando Jardim¹, Mohsen Akbari^{1

5

6}

Affiliations

¹ Laboratory for Innovation in Microengineering (LiME), Department of Mechanical Engineering, Center for Biomedical Research University of Victoria 3800 Finnerty Rd. Victoria BC V8P 2C5 Canada.
² Department of Mechanical and Industrial Engineering University of Toronto Toronto ON M5S 3G8 Canada.
³ Institute of Biomaterials and Biomedical Engineering (IBBME) University of Toronto Toronto ON M5S 3G9 Canada.
⁴ Institute of Biomedical Engineering (BME) Ted Rogers Centre for Heart Research University of Toronto Toronto ON M5G 1M1 Canada.
⁵ Center for Biomedical Research University of Victoria 3800 Finnerty Rd. Victoria BC V8P 2C5 Canada.
⁶ Centre for Advanced Materials and Related Technology (CAMTEC) University of Victoria 3800 Finnerty Rd. Victoria BC V8P 2C5 Canada.

Abstract

Following the emergence of severe acute respiratory syndrome (SARS) in 2002 and the Middle East respiratory syndrome (MERS) in 2012, the world is now combating a third large-scale outbreak caused by a coronavirus, the coronavirus disease 2019 (COVID-19). After the rapid spread of SARS-coronavirus (CoV)-2 (the virus causing COVID-19) from its origin in China, the World Health Organization (WHO) declared a Public Health Emergency of International Concern (PHEIC) on January 30, 2020. From the beginning of the COVID-19 pandemic, a significant number of studies have been conducted to better understand the biology and pathogenesis of the novel coronavirus, and to aid in developing effective treatment regimens, therapeutics, and vaccines. This review focuses on the recent advancements in the rapidly evolving areas of clinical care and management of COVID-19. The emerging strategies for the diagnosis and treatment of this disease are explored, and the development of effective vaccines is reviewed.

Keywords: COVID 19; MERS; SARS; coronavirus disease 2019; treatment strategies.

Publication types

Review