Role of Purinome, A Complex Signaling System, In Glioblastoma Aggressiveness

Front Pharmacol. 2021 Feb 5:12:632622. doi: 10.3389/fphar.2021.632622. eCollection 2021.

Patricia Giuliani^{1

2}, Marzia Carluccio^{1

2}, Renata Ciccarelli^{1

2}

¹ Department of Medical, Oral and Biotechnological Sciences, 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy.
² Center for Advanced Studies and Technology (CAST), 'G. D'Annunzio' University of Chieti-Pescara, Chieti, Italy.

No abstract available

Keywords: adenine-based compounds; glioblastoma multiforme (GBM); purine metabolizing enzymes; purinergic receptors; purinome.