The degenerative diseases in menopause-age women has been continued to increase every year. This study aimed to analyze the relation of body mass index, waist circumference, and body fat percentage on blood biochemical markers of lipid and oxidative stress in menopausal women. This randomized control trial (RCT) was conducted using a cross-over design. The subjects in this study were sixteen menopausal women in Ciherang Village, Dramaga Subdistrict, Bogor, West Java, Indonesia. The data were analyzed using Microsoft Excel program and SPSS 23 software. The results showed that the subjects' mean age was 57±4.63 y with the age range of 50-60 y. The subjects' mean BMI was 27.55±2.11 kg/m2, the mean waist circumference was 90.77±7.16 cm, and the mean body fat percentage was 35.6±3.26%. The mean cholesterol, triglycerides, HDL-c, and LDL-c levels after the intervention were 186.4 mg/dL, 119.8 mg/dL, 55.5 mg/dL, and 107 mg/dL, respectively. The mean MDA and SOD levels were 155.5 ng/mL and 27.55 U/mL, respectively. This study concluded that BMI had significant positive correlations with body fat percentage, cholesterol levels, LDL-c levels, and serum MDA levels. BMI and body fat percentage had significant negative correlations with serum SOD levels.
Keywords: BMI; lipid profile; menopausal women; oxidative stress.