From recipe to research: introducing undergraduate students to the nature of science using a hybrid practical course centred on drug discovery for neglected diseases

Maikel Wijtmans; Ewald Edink; Oscar Pj van Linden; Yang Zheng; Antoni R Blaazer; Marco Siderius; Jacqueline E van Muijlwijk-Koezen

doi:10.1016/j.drudis.2021.02.012

From recipe to research: introducing undergraduate students to the nature of science using a hybrid practical course centred on drug discovery for neglected diseases

Drug Discov Today. 2021 Jun;26(6):1359-1368. doi: 10.1016/j.drudis.2021.02.012. Epub 2021 Feb 18.

Authors

Maikel Wijtmans¹, Ewald Edink², Oscar Pj van Linden³, Yang Zheng⁴, Antoni R Blaazer³, Marco Siderius⁴, Jacqueline E van Muijlwijk-Koezen⁵

Affiliations

¹ Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
² Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands; Current address: Department of Life Sciences and Chemistry, Faculty of Agri, Food and Life Sciences, Inholland University of Applied Sciences, De Boelelaan 1109, 1081 HV Amsterdam, The Netherlands.
³ Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
⁴ Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands.
⁵ Division of Innovations in Human Health and Life Sciences, Amsterdam Institute of Molecular and Life Sciences, Faculty of Science, Vrije Universiteit Amsterdam, De Boelelaan 1108, 1081 HZ Amsterdam, The Netherlands. Electronic address: j.e.van.muijlwijk-koezen@vu.nl.

PMID: 33609778
DOI: 10.1016/j.drudis.2021.02.012

Abstract

A hybrid undergraduate practical course involving synthetic medicinal chemistry on neglected diseases bridges the gap between skills, techniques and scientific research, and exposes students to the nature of science.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biomedical Research / education
Chemistry, Pharmaceutical / education*
Drug Discovery / education*
Humans
Neglected Diseases / drug therapy*
Students