Complete genomic characterization of a new KLRC2 allele, NKG2C*03

HLA. 2021 Sep;98(3):259-261. doi: 10.1111/tan.14231. Epub 2021 Feb 26.

Authors

Judit Asenjo¹, Aura Muntasell^{2

3}, Miguel López-Botet^{3

4}, Manuela Moraru¹, Carlos Vilches¹

Affiliations

¹ Immunogenetics & Histocompatibility Lab, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Madrid, Spain.
² Department of Cell Biology, Physiology and Immunology, Universitat Autonòma de Barcelona, Bellaterra, Spain.
³ Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
⁴ University Pompeu Fabra, Barcelona, Spain.

Abstract

The novel NKG2C*03 allele encodes a hybrid of the NKG2C*01 and NKG2C*02 primary structures.

Keywords: HLA-E; NKG2C receptor; alleles; genetic polymorphism; human genetics; natural killer cell lectin-like receptors.

© 2021 The Authors. HLA: Immune Response Genetics published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Genomics
Humans
Killer Cells, Natural*
NK Cell Lectin-Like Receptor Subfamily C* / genetics

Substances

KLRC2 protein, human
NK Cell Lectin-Like Receptor Subfamily C